3rd Stryker Brigade heading to Afghanistan

Tuesday, 27 August 2013

Joint Base Lewis-Mcchord, Aug 28 (Newswire): The 3rd Stryker Brigade will be deployed to Afghanistan in December, the US Department of Defense announced.

The brigade's 2nd Infantry Division will be part of an upcoming rotation of forces operating in Afghanistan, the DOD said.

Base spokesman Joe Piek said this will be the unit's fourth deployment and its first to Afghanistan. The deployment will involve about 3,200  soldiers.

The unit returned in September 2010 from its most recent mission after spending a year in Ira
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Few treatment options for Afghans as drug use rises

Kabul, Aug 28 (Newswire): Once a river flowed under the low Pul-i-Sokhta bridge here, but now the thin stream is clotted with garbage, the banks are piled with refuse and crowds of heroin and opium addicts huddle in the shadows, some hanging like moths near the bridge's supports, then slumping in the haze of narcotic smoke.

When outsiders venture in, dozens of the addicts — there are 200 or 300 here on any given day — drift over to see the newcomers. Most of the visitors are health care workers trying to persuade the addicts to visit their clinic for a shower and a medical screening.

"Are you taking names for treatment?" one man asks, his soiled salwar kameez hanging loosely around his thin body. "Put me down, my name is Zainullah."

This is another of Afghanistan's afflictions: a growing drug addiction problem and all the ills that come with that, not least H.I.V., the virus that causes AIDS, which can be transmitted when addicts share needles. There were about 900,000 drug users in Afghanistan in 2010, according to the United Nations Office on Drugs and Crime, a marked increase from previous years. That means about 7 percent of the adult population of 14 million is using narcotics.

A vast majority take opium-based drugs, which are extraordinarily pure here and very cheap — about $3.50 for enough to get high, addicts say. Afghanistan is the world's leading producer of opium poppy, and the opium produced and sold here and its derivatives, including heroin, are among the most potent on earth. About 150,000 of those using opium-based drugs are injecting heroin, according to the World Health Organization.

A measure of the problem is that surveys show that 12 to 41 percent of police recruits test positive for some form of narcotic — most are hashish smokers — according to a recent report by the Government Accountability Office.

Another indicator of the problem is a recent report by the Ministry of Public Health in partnership with Johns Hopkins University that found H.I.V. present in about 7 percent of drug users, double the figure just three years ago, said Dr. Fahim Paigham, who until recently directed the Ministry of Public Health's AIDS control program.

Unlike the situation in many countries, where H.I.V. is transmitted primarily through sexual contact, in Afghanistan the primary transmission is through shared needles.

The Pul-i-Sokhta bridge — the name means "burned bridge" — and another bridge nearby are the most recent refuges for many of Kabul's heroin and opium addicts who used to gather in the ruins of the Russian cultural center on the east side of the city. They were forced out in late 2010; although some remained in the neighborhood, many came to the bridges.

Some come here every day to buy and use narcotics, crouching in the dark corners to shoot up or gathering in small groups to heat the opium powder until it melts into a black liquid and gives off smoke to inhale.

The ground under the bridge is thick with discarded syringes. Six mornings a week a team of former addicts, nurses and a couple of social workers from the French group Médecins du Monde (Doctors of the World), a nonprofit health care organization, forge ahead into this particular circle of hell, with large plastic disposal jugs in one hand and long-handled pincers in the other to pluck needles from the garbage. It is not uncommon to pick up 160 or 170 needles in a morning. They hand out fresh needles and alcohol swabs, and the nurse treats the addicts' seeping wounds where they have injected themselves too many times.

Not all the addicts are sure they can tolerate treatment, and some are so high they often make little sense. "I am the Bobby Devil of this town," said a tall, bony young man in aviator glasses, cargo pants and a plaid cotton shirt, who was sprawled next to a small group smoking heroin, but had propped himself up on his elbows to talk. Bobby Devil is the stage name of an Indian actor well known here for his action movies.

"I've been using for four years," he added. "Last night I went home with money and fresh fruit, and my wife and children told me to go away. They said, 'You are a drug addict, you are a dog.' "

Could he quit? "Well, I can't decide; both my wife and the drug are strong," he said and lay back down.

Many of the addicts say they want to stop using, but treatment options are woefully few. The government, through some Afghan nonprofit groups, runs several detoxification centers and is building seven more, but the facilities offer almost no post-detoxification support and have a 92 percent relapse rate, according to the Ministry of Counternarcotics, which is involved in running them. The most efficacious treatment — opiate substitution therapy — has been all but blocked by the ministry despite pleas from the Ministry of Public Health, whose doctors are worried about the rising incidence of H.I.V.

"The results from opiate substitutes like methadone are very positive," Dr. Paigham said.

"If you stop using heroin, you stop using the needles, and if you stop using the needles there is much less risk of spreading H.I.V."

Methadone is typically given in syrup form here. However, officials at the Ministry of Counternarcotics are leery of it because the opiate substitutes do not cure addiction.

"It is the view in Afghanistan, it is just substituting one addiction for another," said Mohammed Ibrahim, the deputy minister of counternarcotics.

The ministry undermined the country's sole opiate substitution effort, a pilot program run by Médecins du Monde that administers methadone to 70 addicts. The program has been strongly endorsed by the World Health Organization as well as by participants, and it has a waiting list. However, the ministry twice blocked the import of the methadone, making it all but impossible for the heavily addicted participants to stick with the program.

For now the pilot program is running, but it has not been permitted to expand.

This year the number of drug addicts is expected to rise. Many Afghans start using narcotics when they seek work in Iran, which has one of the worst drug problems in the region. Increasingly, Iran is expelling addicted Afghans, shipping them back across the border. A few Afghan addicts say they were trying to quit while in Iran, which has a comprehensive system of methadone clinics which provide the drug, but most cannot imagine a way out.

"I started using in Iran from depression and sadness," said Zainullah, 19, a Hazara man from Ghazni Province. "I was alone. There was no one in Iran from my family. I went there to find work, and I started smoking heroin."

He returned to his farming village and his nine siblings six months ago, but a month later came to Kabul.

"Nobody likes a drug addict, so my family sent me here to quit," he said, speaking softly. "Instead, here I am under the bridge, and I have increased my dose since I came.

"If you could help me, please," he said, raising his thin arms as if beseeching the aid workers. "I don't know how to stop."
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In helping Afghanistan build up its security forces, US is trimming the frills

Mehterlam, Aug 28 (Newswire): The commander of NATO's elaborate and expensive effort to build the Afghan security forces, Lt. Gen. William B. Caldwell, was standing inside the bathroom of a police training school in this obscure eastern town, looking at the sinks. He did not like what he saw.

"Every time I walk into someplace and see a porcelain sink, I cringe," he said.

That's because Caldwell is tasked with making the Afghan army and police capable of holding off the Taliban — but in a way the United States can afford. Growing political concern in the United States over the high cost of the American mission has made for a blunt new imperative: The Afghan security forces, which cost the United States $11.6 billion this year, need to get cheaper — fast.

To this end, out are the pedestal porcelain sinks in the bases the United States is building for the Afghan army and police; in are communal metal troughs. Out: air conditioning. In: ceiling fans. Out: brick-and-mortar barracks. In: quick-rising steel "arch-span" buildings.

"If they can't afford it and sustain it in 2014" — the year Afghan security forces are scheduled to be in charge of their own destiny — "we don't build it," Caldwell said.

The scope of the U.S.-funded building boom for Afghan security forces nevertheless remains immense. Contractors are about a quarter of the way through a $11.4 billion effort to erect 10,000 buildings — about 100 bases for the Afghan army and nearly 1,000 sites for the police — though a large number of projects are expected to be completed by spring. They range from small police outposts to the $200 million National Defense University in Kabul.

This effort began in earnest just a couple of years ago, when U.S. officials made training and equipping the Afghan security forces a top priority. Soon some of the more glaring cultural differences became apparent, said Maj. Gen. Peter Fuller, the deputy commander for programs with NATO's training command in Kabul.

Some Afghans were unaccustomed to Western-style toilets, for example, and would perch, squatting, on the rim of the seat, mimicking how they used the hole-in-the-floor style more common here. When gas was in short supply, some tried to convert the NATO-supplied propane stoves into wood-burning ones, with little success.

"What we're trying to do is realize how would the Afghans operate if they were to go out and contract for a building," Fuller said. "Let's make things appropriate for Afghanistan. We call it 'Afghan right.'?"

Not by coincidence, these new construction standards, revised this year, also are cheaper. Just by eliminating most air conditioning in Afghan military and police bases, NATO officials estimate they are saving more than $100 million a year on fuel. The pared-down standards also result in simpler structures that NATO officials hope are more likely to be kept up after coalition troops depart.

"We're teaching them something that's a lot simpler, and certainly they understand," said Col. Mario A. Trevino, a NATO engineer in Kabul.
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Smoking soon after waking raises risk of lung and head and neck cancers

Islamabad, Aug 28 (Newswire): Two new studies have found that smokers who tend to take their first cigarette soon after they wake up in the morning may have a higher risk of developing lung and head and neck cancers than smokers who refrain from lighting up right away.

The findings by researchers at Columbia University's Mailman School of Public Health and Penn State College of Medicine may help identify smokers who have an especially high risk of developing cancer and would benefit from targeted smoking interventions to reduce their risk.

Cigarette smoking increases one's likelihood of developing various types of cancers. But why do only some smokers get cancer? The researchers investigated whether nicotine dependence as characterized by the time to first cigarette after waking affects smokers' risk of lung and head and neck cancers independent of cigarette smoking frequency and duration.

The lung cancer analysis included 4,775 lung cancer cases and 2,835 controls, all of whom were regular cigarette smokers. Compared with individuals who smoked more than 60 minutes after waking, individuals who smoked 31 to 60 minutes after waking were 1.31 times as likely to develop lung cancer, and those who smoked within 30 minutes were 1.79 times as likely to develop lung cancer.

The head and neck cancer analysis included 1,055 head and neck cancer cases and 795 controls, all with a history of cigarette smoking. Compared with individuals who smoked more than 60 minutes after waking, individuals who smoked 31 to 60 minutes after waking were 1.42 times as likely to develop head and neck cancer, and those who smoked within 30 minutes were 1.59 times as likely to develop head and neck cancer.

These findings indicate that the need to smoke right after waking in the morning may increase smokers' likelihood of getting cancer. "These smokers have higher levels of nicotine and possibly other tobacco toxins in their body, and they may be more addicted than smokers who refrain from smoking for a half hour or more," said Joshua Muscat, PhD, of the Penn State College of Medicine in Hershey and first author. "It may be a combination of genetic and personal factors that cause a higher dependence to nicotine."

Dr. Steven D. Stellman, professor of clinical epidemiology at the Mailman School of Public Health and director of the overall research program under which the data were gathered, stated, "Our finding that time to first cigarette raises the risk of cancer is the latest in a long series of studies that grew directly out of Dr. Ernst Wynder's work, published in JAMA, which first described the link between cigarette smoking and lung cancer. Research has steadily expanded our knowledge of the hazards of tobacco use."

According to the authors, because smokers who light up first thing in the morning are a group that is at even higher risk of developing cancer than other smokers, they would benefit from targeted smoking cessation programs. Such interventions could help reduce tobacco's negative health effects as well as the costs associated with its use.
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Differences in metabolic disease markers in healthy and obese 7-to-9-year-olds identified

Islamabad, Aug 28 (Newswire): Research led by Dr. Melinda Sothern, Professor of Public Health and Jim Finks Endowed Chair in Health Promotion at LSU Health Sciences Center New Orleans, has found that obese 7-9-year-old children had nearly three times the liver fat and almost double the belly fat of their nonobese counterparts and that insulin resistance was more than double and insulin sensitivity less than half respectively.

The study is the first to use a combination of advanced measurements in healthy obese and nonobese children in this age group prior to entering puberty.

"The amount of body fat as well as its location, particularly in the liver, appears to play a critical role in disease development," notes LSUHSC's Dr. Melinda Sothern. "The substantial variation in biomarkers we observed in these young children suggests that obesity in this age group may disrupt normal metabolism, impairing glucose tolerance and increasing the risk for Type 2 diabetes later in life."

The researchers studied 123 children, ages 7-9, recruited from southeast Louisiana. By BMI z-score thresholds, 23.6% of the children were obese. Although a clear definition for the metabolic syndrome in children and adolescents has not yet been established, by one set of proposed criteria, 16% of participants met the definition, and 8% met the criteria by another definition.

"Our data confirm that healthy obese young children may already be predisposed to the development of metabolic disease as has been demonstrated in adult populations," said Dr. Sothern. "Our findings highlight the importance of interventions to prevent and manage obesity very early in life and suggest this is a possible means of reducing metabolic disease risk and combating the increasing prevalence of Type 2 diabetes."

Over the past 30 years, the prevalence of obesity has increased considerably. Although a recent national report indicates a leveling off of this trend, a significant portion of the pediatric population remains obese and at risk for developing metabolic diseases, particularly those related to carbohydrate metabolism. Some regions, especially areas with traditionally higher obesity prevalence rates, however, may not mirror national estimates.

The research team also included Drs. Julia Volaufova, William Cefalu, Stuart Chalew, Stewart Gordon, and Arlette Soros as well as Brian Bennett at LSU Health Sciences Center; Drs. Eric Ravussin, and Steve Smith at LSU's Pennington Biomedical Research Center, as well as Dr. Enette Larson-Meyer at the University of Wyoming; Dr. Bradley Newcomer at the University of Alabama at Birmingham; and Dr. Michael Goran at the University of Southern California.
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Few health problems are caused by vaccines

Islamabad, Aug 28 (Newswire): An analysis of more than 1,000 research articles concluded that few health problems are caused by or clearly associated with vaccines.

A committee of experts convened by the Institute of Medicine to review the scientific literature on possible adverse effects of vaccines found convincing evidence of 14 health outcomes -- including seizures, inflammation of the brain, and fainting -- that can be caused by certain vaccines, although these outcomes occur rarely.

It also found indicative though less clear data on associations between specific vaccines and four other effects, such as allergic reactions and temporary joint pain.

In addition, the evidence shows there are no links between immunization and some serious conditions that have raised concerns, including Type 1 diabetes and autism. The data were inadequate to reach conclusions about other suggested adverse effects.

The review will help the U.S. Department of Health and Human Services (HHS) administer the Vaccine Injury Compensation Program (VICP). VICP is committed to using science-based evidence to inform its decisions about vaccine-related adverse effects, and HHS turned to IOM to provide a comprehensive review of study results on eight vaccines covered by the program. The report's findings will be useful to all stakeholders involved in vaccine compensation decisions, including VICP staff, people filing claims, special masters that rule on vaccine cases, and others.

Convincing evidence shows that the measles-mumps-rubella (MMR) vaccine can lead to fever-triggered seizures in some individuals, although these effects are almost always without long-term consequences, the report says.

The MMR vaccine also can produce a rare form of brain inflammation in some people with severe immune system deficiencies. In a minority of patients, the varicella vaccine against chickenpox can induce brain swelling, pneumonia, hepatitis, meningitis, shingles, and chickenpox in immunocompromised patients as well as some who apparently have competent immune function, the committee found.

The majority of these problems have occurred in individuals with immunodeficiencies, which increase individuals' susceptibility to the live viruses used in MMR and varicella. Six vaccines -- MMR, varicella, influenza, hepatitis B, meningococcal, and the tetanus-containing vaccines -- can trigger anaphylaxis, an allergic reaction that appears shortly after injection. And, in general, the injection of vaccines can trigger fainting and inflammation of the shoulder, the committee noted.

The evidence suggests that certain vaccines can lead to four other adverse effects, although the data on these links are not as convincing, the report says. The MMR vaccine appears to trigger short-term joint pain in some women and children. Some people can experience anaphylaxis after receiving the HPV vaccine. And certain influenza vaccines used abroad have resulted in a mild, temporary oculo-respiratory syndrome characterized by conjunctivitis, facial swelling, and mild respiratory symptoms.

The committee's review also concluded that certain vaccines are not linked to four specific conditions. The MMR vaccine and diphtheria-tetanus-acellular pertussis (DTaP) do not cause Type 1 diabetes, and the MMR vaccine does not cause autism, according to the results of several studies. The evidence shows that the flu shot does not cause Bell's palsy or exacerbate asthma. Suggestions that vaccines can lead to these serious health problems have contributed to parental concerns about immunization for their children.

Establishing a cause-and-effect relationship between an agent and a health outcome requires solid evidence.

The committee's conclusions are based on the strengths and weaknesses of several types of evidence, including biological, clinical, and epidemiological research. In many cases of suggested vaccine-related adverse outcomes, there is too little evidence, or the available evidence offers conflicting results or is otherwise inadequate to draw conclusions.

"With the start of the new school year, it's time to ensure that children are up to date on their immunizations, making this report's findings about the safety of these eight vaccines particularly timely," said committee chair Ellen Wright Clayton, professor of pediatrics and law, and director, Center for Biomedical Ethics and Society, Vanderbilt University, Nashville, Tenn.

"The findings should be reassuring to parents that few health problems are clearly connected to immunizations, and these effects occur relatively rarely. And repeated study has made clear that some health problems are not caused by vaccines."

In accordance with its charge, the committee focused solely on findings about potential risks of immunizations. It did not examine information that would have allowed it to draw conclusions about the ratio of benefits to risks. However, the committee members noted that deaths and disability due to infectious diseases have been dramatically reduced over the last century since the majority of vaccines were developed and brought into widespread use.
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